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DANA C. PENTIA

EDUCATION:
1991-1996 University of Bucharest B.S. in Biochemistry
EMPLOYMENT:
1996-1997 Biology teacher High School "Horia Hulubei", Bucharest, Romania
1997-2000 Research Assistant Bio-thermodynamics lab, Institute of Physical Chemistry of the Romanian Academy

PRIOR RESEARCH EXPERIENCE:

  • Univeristy of Bucharest, Department of Physical Chemistry, Romania. 1993-2000. Kinetics of Photo-bleaching of Violamycin B1. Research advisors: Dr. Tatiana Onescu and Dr. Savu-Gheorghe Ionescu.
  • Institute of Physical Chemistry of the Romanian Academy, Biothermodynamics Laboratory, Bucharest, Romania. 1997-2000. Calorimetric determination of the oxidative stress induction in Saccharomyces Cerevisiae. Research advisor: Dr. Cristian Telea.
  • University of New Hampshire, Durham, NH. 2000-present. Purification of the Photoreceptor Glutamic Acid-Rich Protein 2 and Characterization of its Interaction with the Photoreceptor Phosphodiesterase 6. Research Advisor: Dr. Rick Cote.

PUBLICATIONS:
Pentia, D.C., Hosier, S., Collupy, R.A., Valeriani, B.A. and Cote,R.H. (2005). Purification of PDE6 isozymes from mammalian retina. Methods in Molecular Biology, 307,125-40.

Pentia, D.C., Hosier, S., Cote, R.H. (2006) Glutamic Acid-Rich Protein 2 (GARP2) is a High-Affinity Rod Phosphodiesterase6 (PDE6)-Binding Protein that Modulates its Catalytic Properties. Journal of Biological Chemistry, 281(9): 5500-5.

Pentia, D.C., Cote, R.H. (2006) Glutamic Acid-Rich Protein 2 Determines the Binding Affinity of Phosphodiesterase 6 Inhibitory Subunit in a Light Dependent Fashion. Journal of Biological Chemistry, in preparation.

ABSTRACTS AND PRESENTATIONS AT SCIENTIFIC MEETINGS:
T. Oncescu, S.G. Ionescu, and D. Pentia, The influence of irradiation parameters on the photodegradation of violamycin BI, presented at 9th International Conference on Physical Chemistry, Galati, Romania, 1998

Pentia, D. C. and Cote, R. H. Characterization of rod photoreceptor glutamic acid-rich protein interactions with rod photoreceptor PDE6. Ass.Res.Vision Ophthalmol. 03-A-4263. 2003.

TEACHING EXPERIENCE:
1996 - 1997, High school Biology teacher
2000 - 2002, Teaching Assistant for General Biochemistry Lab (BCHM 659)

CONTACT INFORMATION:

PHONE: 603-862-3829
FAX: 603-862-4013
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