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KARYN CAHILL

 

 
EDUCATION:
St. Joseph College B.S. Biology/Biochemistry
University of Connecticut Health Center Ph.D. Molecular Biology
EMPLOYMENT:
Bayer Pharmaceutical West Haven, CT

PRIOR RESEARCH EXPERIENCE:

Cloning and expression of genes from various therapeutic areas (cancer, diabetes, obesity, Alzheimer's) to produce functional protein for high throughput screening assays.

PUBLICATIONS:

Cahill, K., Altman, R.A., Donaldson, T., Rocks, S., Tyler, M. and D.O. Wirak. Development of transgenic mouse models for Alzheimer's disease using a novel gene-targeting strategy. Bayer Pharma Report (1996)

Altman, R.A., Cahill, K., and D.O. Wirak. Swedish FAD mutation alters the processing of APP in transgenic animals. Bayer Pharma Report (1996)

Cahill, K.B., Wirak, D.O., Mierz, D.V., Wunderlich, D.A., Rose, B.W., Shedd, D.G., Gillespie, A., and B.R. Zerler. Transgenic mice and transhybridomas producing chmeric mouse.human anti-human interleukin-2 receptor recombinant antibodies. Gene:137:101-107 (1993)

Rose, B., Gillespie, A., Wunderlich, D., Barbosa, J.A., Cahill, K., Dziuba, J., Shedd, D., and B. Zerler. A chimeric mouse/human anti-IL-2 receptor antibody with enhanced biological activities. Molec. Immunol:29:131-144 (1992)

Rose, B., Gillespie, A., Wunderlich, D., Kelley, K., Dziuba, J., Shedd, D., Cahill, K., and B. Zerler. Differential effects of a murine and chimeric mouse/human anti-interleuken-2 receptor antibody on human T-cell proliferation. Immunol.:76:452-459 (1992)

Cahill, K.B., Roome, A.J., and G.G. Carmichael. Replication dependent transactivation of the polyomavirus late promoter. J.Virol.:64:992-1001 (1990)

Cahill, K.B., and G.G. Carmichael. Deletion Analysis of the polyomavirus late promoter: Evidence for both positive and negative elements in the absence of early proteins. J. Virol.:63:3634-3642 (1989)

Klobutcher, L.A., Valonis-Walsh, A.M., Cahill, K., and R.M. Ribas-Aparicio. Gene-sized macronuclear DNA molecules clustered in micronuclear chomosomes of the ciliate oxytricha nova. Molec. Cell. Biol.:6:3606-3613. (1986)

PUBLISHED ABSTRACTS:

Wiebringhaus, T., Wirak, D., Altman, R., Cahill, K., Duff, K., Ruhland, M., Konig, G., and K. Baumann. The effect of Presenilin on beta-amyloid in knock-in mice carrying the human amyloid precursor protein with Swedish and/or London mutatuion, World Alzheimer Congress 2000, Washington, D.C. ( 2000)

Altman, R.A., Cahill, K.B., Davis, A.C., Donaldson, T.E., Rocks, S.B., Tyler-Bauchman, M.K., and D.O. Wirak. A novel gene targeting technique: Introduction of Swedish and London Familial Alzheimer's Disease (FAD) mutations into the mouse gene for the Amyloid Precursor Protein (APP), 27th Annual Meeting, Society for Neuroscience, New Orleans, LA. (1997)

AWARDS:

TEACHING EXPERIENCE:

CONTACT INFORMATION:

PHONE: 603-862-3829
FAX: 603-862-4013
EMAIL: